Viral Particles in Microscopy

Colorized transmission electron micrographs showcasing various viruses, including Hepatitis B, HIV-1, and SARS-CoV-2, against vibrant, abstract backgrounds.

Transmission electron micrograph of dengue virus particles (gold).

Hepatitis B virus (Hepadnavirid family). HBV causes sexually transmitted or blood-borne hepatitis. Cirrhosis occurs in 20% of cases 15 to 20 years after the onset of infection. Image made from transmission electron microscopy. Approximate viral diameter: 22 nm.

Togavirus. Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter around 100 nm.

Transmission electron micrograph of HIV-1 virus particles (colorized pink/yellow) replicating from an HIV-infected H9 T-cell (brown).

Epstein-Barr virus (human herpesvirus 4, HHV-4). It causes infectious mononucleosis and Burkitt's lymphoma. View taken with HDRI image processing from a transmission electron microscopy image. Viral diameter about 200 nm.

Transmission electron micrograph of SARS-CoV-2 virus particles (green) within endosomes of a heavily infected nasal Olfactory Epithelial Cell. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland.

Hepatitis B virus. Color enhanced Transmission Electron Micrograph (TEM) of the Hepatitis B virus (HBV, Hepadnaviridae).

Transmission electron micrograph of dengue virus particles (gold).

This transmission electron micrograph (TEM) depicted numbers of intact rotavirus double-shelled particles. Note the distinctive rim of radiating capsomeres.

Hepatitis C virus (close to the Flavivirid family). HCV causes blood-borne hepatitis, cirrhosis occurs in 25% of cases, 10 to 20 years after the onset of infection, with a risk of hepatic carcinoma. Image made from transmission electron microscopy. Approximate viral diameter: 50 to 60 nm.

Varicella zoster virus (human herpesvirus type 3, HHV-3). It causes chicken pox and shingles (herpes zoster). Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter around 200 nm.

Transmission electron micrograph of HIV-1 virus particles (pink) replicating from the plasma membrane of an infected H9 T cell.

Transmission electron micrograph (TEM) of human herpes virus-6 (HHV-6) previously called HBLV (human b-lymphotropic virus). It infects lymphocyte T cells as well. It is the cause of the childhood rash roseola and some cases of mononucleosis.

Coronavirus. Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter ranges from around 80 to 160 nm.

Negatively-stained transmission electron micrograph of Hong Kong flu virus virions

Human papilloma virus (HPV). Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter around 55 nm.

This colorized negative-stained transmission electron micrograph (TEM) depicts the ultrastructural details of a number of influenza virus particles, or virions. A member of the taxonomic family Orthomyxoviridae, the influenza virus is a single-stranded RNA organism. The flu is a contagious respiratory illness caused by influenza viruses. It can cause mild to severe illness, and at times can lead to death. The best way to prevent this illness is by getting a flu vaccination each fall.

Heptatitis E virus. Electron micrograph of Hepatitis E viruses (HEV). Formerly a RNA virus member of the Caliciviridae, HEV are now classified as Hepeviridae.

Adenovirus (highly contagious virus causing lymphadenopathy symptomatizing swelling of the glands in the neck, accompanied by a cold, or pharyngitis, or bronchitis, sometimes also conjunctivitis, keratitis, or a combination of the two (keratoconjunctivitis). View produced from a transmission electron microscopy view. Viral diameter approximately: 80 to 110 nm.

Hepatitis C virus (close to the Flavivirid family). HCV causes blood-borne hepatitis, cirrhosis occurs in 25% of cases, 10 to 20 years after the onset of infection, with a risk of hepatic carcinoma. View produced from a transmission electron microscopy image. Viral diameter approximately: 50 to 60 nm.

A transmission electron micrograph of smallpox viruses using a negative stain technique. Smallpox is a serious, highly contagious, and sometimes fatal infectious disease. There is no specific treatment for smallpox disease

Hepatitis B virus (Hepadnavirid family). HBV causes sexually transmitted or blood-borne hepatitis. Cirrhosis occurs in 20% of cases 15 to 20 years after the onset of infection. Image made from transmission electron microscopy. Approximate viral diameter: 22 nm.

Tacaribe virus (New World Arenavirus). Electron micrograph of Arenaviridae. Arenaviridae are RNA viruses whose particles are spherical and have an average diameter of 110-130 nanometers. Arenaviridae members are zoonotic, which means that in nature they are found in reservoir animal hosts.

Human papilloma virus. Colored transmission electron micrograph (TEM) of human papillomavirus (HPV). The HPV is involved in the development of cervical cancers.

Negatively-stained transmission electron micrograph, TEM, of La Crosse, LAC, encephalitis virus Ribonucleoprotein Particles

Adenovirus (highly contagious virus), responsible for: Colds, pharyngitis, bronchitis, pneumonia, gastroenteritis, conjunctivitis and keratitis. Image made from a transmission electron microscopy view.

Varicella Virus

This colorized transmission electron micrograph (TEM) revealed some of the ultrastructural morphology displayed by norovirus virions, or virus particles.

Rotavirus. Rotavirus is the primary cause of severe diarrhoea in young children worldwide. Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter ranges from around 60 to 80 nm.

Arenavirus. Arenaviruses cause several types of viral hemorrhagic fever (New World fevers). The viruses are transmitted to humans by rodents and bats. Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter ranges from around 110 to 130 nm.

Coronavirus (CoV). viruses of the Coronaviridae family and the Orthocoronavirinae subfamily. It is a pathogen of respiratory syndromes. Viewed from a transmission electron microscopy (TEM) image. Viral diameter 80nm to 100nm.

Colorized transmission electron micrograph of monkeypox virus particles (gold) cultivated and purified from cell culture.

Virus responsible for smallpox. A transmission electron micrograph of smallpox viruses. Smallpox is a serious, highly contagious, and sometimes fatal infectious disease. There is no specific treatment for smallpox disease, and the only prevention is vaccination. See image n0641905 on the site.

Togavirus. Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter around 100 nm.

This colorized negative-stained transmission electron micrograph (TEM) depicts the ultrastructural details of a number of influenza virus particles, or virions. A member of the taxonomic family Orthomyxoviridae, the influenza virus is a single-stranded RNA organism. The flu is a contagious respiratory illness caused by influenza viruses. It can cause mild to severe illness, and at times can lead to death. The best way to prevent this illness is by getting a flu vaccination each fall.

Adenovirus (highly contagious virus), responsible for: Colds, pharyngitis, bronchitis, pneumonia, gastroenteritis, conjunctivitis and keratitis. Image made from a transmission electron microscopy view.

Transmission Electron Micrograph (TEM) of Spanish flu virus. This pandemic virus infected a fifth of the world population and killed between 20 and 50 million. This Influenza virus type a, strain H1N1 is very close to the swine flu (strain H1N1) and the avian flu virus (strain H5N1).

Human papilloma virus (HPV). Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter around 55 nm.

This colorized negative stained transmission electron micrograph of the A/CA/4/09 swine flu virus. 2009 photo by C. S. Goldsmith and A. Balish.

The mumps virus (paramyovirus). Image produced with transmission electron microscope (viral diameter around 200 nm).

Colorized transmission electron micrograph of monkeypox virus particles (gold) cultivated and purified from cell culture

Herpes virus (HSV 1 and 2). View taken with HDRI image processing from a transmission electron microscopy image. Viral diameter about 200 nm.

Varicella zoster virus (VZV or HHV 3). Image taken with transmission electron microscopy.

Hepatitis A virus (HAV). Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter ranges from around 20 to 30 nm.

This colorized transmission electron micrograph (TEM) of an ultra-thin specimen revealed some of the ultrastructural morphologic features seen in 1918 influenza virus virions. The prominent surface projections on the virions are composed of either the hemagglutinin, or neuraminidase type of glycoproteins. Composed of what looked like dots or tubules, was a dense envelope known as a capsid, which surrounded each virion's nucleic acid constituents.

2009 C. S. Goldsmith and A. Balish This preliminary negative stained transmission electron micrograph (TEM) depicted some of the ultrastructural morphology of the A/CA/4/09 swine flu virus. See PHIL 11213 for a black and white version of this image. What is Swine Influenza Swine Influenza (swine flu) is a respiratory disease of pigs caused by type A influenza virus that regularly causes outbreaks of influenza in pigs. Swine flu viruses cause high levels of illness and low death r

This colorized negative stained transmission electron micrograph (TEM) depicted some of the ultrastructural morphology of the A/CA/4/09 swine flu virus. Swine Influenza (swine flu) is a respiratory disease of pigs caused by type A influenza virus that regularly causes outbreaks of influenza in pigs. Swine flu viruses cause high levels of illness and low death rates in pigs. Swine influenza viruses may circulate among swine throughout the year, but most outbreaks occur during the late fall and winter months similar to outbreaks in humans. The classical swine flu virus (an influenza type A H1N1 virus) was first isolated from a pig in 1930.

Picornavirus (picornavirid), responsible for: Colds, gastroenteritis, poliomyelitis and meningitis. Image made from a transmission electron microscopy view.

Flavivirus (family Flaviviridae), these viruses are responsible for yellow fever, dengue fever, Japanese encephalitis, Zika virus, West Nile encephalitis. They are transmitted by mosquitoes or ticks. image produced from transmission electron microscopy (viral diameter approximately 40 to 60 nm).

H3N2 influenza virus particles, TEM

Colorized transmission electron micrograph of monkeypox virus particles (blue) cultivated and purified from cell culture

Transmission electron micrograph of SARS-CoV-2 virus particles (colorized orange), isolated from a patient sample.

Transmission electron microscopic (TEM) image of Marburg virus virions.

Hepatitis D virus (HDV). Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter around 35 nm.

This highly-magnified, digitally-colorized transmission electron micrograph (TEM) depicted numbers of virions from a Novel Flu H1N1 isolate. 2009 H1N1 (sometimes called swine flu) is a new influenza virus causing illness in people. This new virus was first detected in people in the United States in April 2009. This virus is spreading from person-to-person worldwide, probably in much the same way that regular seasonal influenza viruses spread. On June 11, 2009, the World Health Organization (WHO) reported that a pandemic of 2009 H1N1 flu was underway.

Transmission electron micrograph (TEM) of measles virus. This RNA virus is a paramyxovirus, of the genus Morbillivirus.

Human papilloma virus. Colored transmission electron micrograph (TEM) of human papillomavirus (HPV). The HPV is involved in the development of cervical cancers.

Cytomegalovirus (CMV), it causes a mononucleosis syndrome. Image taken from transmission electron microscopy (viral diameter of 200 nm).

Human papilloma virus (HPV). Image produced using high-dynamic-range imaging (HDRI) from an image taken with transmission electron microscopy. Viral diameter around 55 nm.

Adenovirus (highly contagious virus), responsible for: Colds, pharyngitis, bronchitis, pneumonia, gastroenteritis, conjunctivitis and keratitis. Image made from a transmission electron microscopy view.

H3N2 influenza virus particles, TEM

Fluvirus - Influenza virus or Influenza virus. The influenza virus causes the seasonal flu, with in humans, a set of symptoms associating: fever, headache, cough, pharyngitis, myalgia, asthenia and anorexia. View produced from a transmission electron microscopy view. Viral diameter approximately: 80 to 120 nm.

This colorized negative stained transmission electron micrograph (TEM) depicted some of the ultrastructural morphology of the A/CA/4/09 swine flu virus. Swine Influenza (swine flu) is a respiratory disease of pigs caused by type A influenza virus that regularly causes outbreaks of influenza in pigs. Swine flu viruses cause high levels of illness and low death rates in pigs. Swine influenza viruses may circulate among swine throughout the year, but most outbreaks occur during the late fall and winter months similar to outbreaks in humans. The classical swine flu virus (an influenza type A H1N1 virus) was first isolated from a pig in 1930.

Influenza B virus particles, colorized red, gold, and green, isolated from a patient sample and then propagated in cell culture. Both influenza A and B can cause seasonal flu however, unlike influenza A virus, which can also infect animals, influenza B only infects humans.

Colorized transmission electron micrograph of monkeypox virus particles (gold) cultivated and purified from cell culture

Coronavirus (CoV). viruses of the Coronaviridae family and the Orthocoronavirinae subfamily. It is a pathogen of respiratory syndromes. Viewed from a transmission electron microscopy (TEM) image. Viral diameter 80nm to 100nm.

West Nile virus is transmitted to humans through the bite of an infected mosquito. An electron micrograph of the West Nile virus. West Nile virus is a flavivirus commonly found in Africa, West Asia, and the Middle East. It is closely related to St. Louis encephalitis virus found in the United States. The virus can infect humans, birds, mosquitoes, horses and some other mammals.

Colorized transmission electron micrograph of monkeypox virus particles (gold) cultivated and purified from cell culture.

Influenza virus (from the Orthomyxoviridae family and the Influenzavirus genus). Image made from a transmission electron microscopy view.

This transmission electron micrograph (TEM) depicted numbers of intact rotavirus double-shelled particles. Note the distinctive rim of radiating capsomeres.

Hepatitis A virus (picornavirus). HAV causes a hepatitis that is almost always benign. Image made from transmission electron microscopy. Approximate viral diameter: 30 nm.

Lassa virus. Transmission electron micrograph (TEM) of the Lassa virus. The single-stranded RNA virus (Arenaviridae) causes Lassa fever which occurs in West Africa.

Fluvirus - Influenza virus or Influenza virus. The influenza virus causes the seasonal flu, with in humans, a set of symptoms associating: fever, headache, cough, pharyngitis, myalgia, asthenia and anorexia. View produced from a transmission electron microscopy view. Viral diameter approximately: 80 to 120 nm.

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical extracellular viral particles contain cross-sections through the viral genome, seen as black dots.

Colorized transmission electron micrograph of mature extracellular Nipah virus particles (pink) near the periphery of an infected VERO cell (green).

An electron micrograph of the West Nile virus. West Nile virus is a flavivirus commonly found in Africa, West Asia, and the Middle East. It is closely related to St. Louis encephalitis virus found in the United States. The virus can infect humans, birds, mosquitoes, horses and some other mammals. Photo by Cynthia Goldsmith.

West Nile virus. Electron micrograph of the West Nile virus. This RNA virus is a flavivirus (flaviviridae) responsible for the West Nile fever.

Marburg virus seen under a transmission electron microscope.

Colorized transmission electron micrograph of monkeypox particles (yellow) found within an infected cell (green), cultured in the laboratory.

Smallpox virus. Transmission Electron Micrograph (TEM) of smallpox viruses.

Flavivirus (family Flaviviridae), these viruses are responsible for yellow fever, dengue fever, Japanese encephalitis, Zika virus, West Nile encephalitis. They are transmitted by mosquitoes or ticks. image produced from transmission electron microscopy (viral diameter approximately 40 to 60 nm).

Colorized TEM image of human white blood cells

Coronavirus (CoV). viruses of the Coronaviridae family and the Orthocoronavirinae subfamily. It is a pathogen of respiratory syndromes. Viewed from a transmission electron microscopy (TEM) image. Viral diameter 80nm to 100nm.

This digitally-colorized transmission electron micrograph (TEM) revealed the presence of a number of infectious bronchitis virus (IBV) virions, which are Coronaviridae family members, and members of the genus Coronavirus. IBV is a highly contagious pathogen, which infects poultry of all ages, affecting a number of organ systems including the respiratory and urogenital organs. IBV is categorized as a Group 3 coronavirus member, with a helical genome composed of positive-sense single-stranded RNA ((+) ssRNA). This is an enveloped virus, which means that its outermost covering is derived from the host cell membrane. The coronavirus derives its name from the fact that under electron microscopic examination, each virion is surrounded by a corona or halo. This is due to the presence of viral spike peplomers emanating from its proteinaceous capsid.

Human herpes virus (HHV), image made from transmission electron microscopy. VHH 1: causes cold sores. VHH 2: causes genital herpes. VHH 3: causes chickenpox and shingles. VHH 4 or EBV: causes infectious mononucleosis and Burkitt's lymphoma. VHH 5 or cytomegalovirus (CMV): causes mononucleosis syndrome. VHH 6: causes roseola. VHH 7: also causes roseola. VHH 8: causes Kaposi's sarcoma and lymph node cancer.

TEM image of coronavirus, the causative agent of SARS

Colorized transmission electron micrograph of a single Nipah virus particle (center, colorized red) that has budded from the surface of an infected cell (green). Nipah virus surface glycoproteins have been labeled using a technique called immunogold labeling in which gold particles (yellow) are bound to antibodies that recognize a specific viral antigen or epitope, which then bind to that individual virus species both within and on the surfaces of infected cells, allowing researchers to see the antibodies and confirm the virus type in the image.

HIV virus. Image produced from an image taken with transmission electron microscopy. Viral diameter around 110 to 125 nm.

Transmission electron micrograph of SARS-CoV-2 virus particles (colorized gold), isolated from a patient sample.

Transmission electron micrograph (TEM) of parainfluenza virus. This RNA virus of the paramyxovirus class causes minor respiratory infections.

Transmission electron micrograph of cytomegalovirus (CMV) particles (red) found within intracellular vesicles of an infected macrophage (blue).

Reovirus, illustration

Transmission electron micrograph of soy bean root

Hepatitis B virus. Color enhanced Transmission Electron Micrograph (TEM) of the Hepatitis B virus (HBV, Hepadnaviridae).

Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland

Virus responsible for smallpox. A transmission electron micrograph of smallpox viruses. Smallpox is a serious, highly contagious, and sometimes fatal infectious disease. There is no specific treatment for smallpox disease, and the only prevention is vaccination.

This electron micrograph depicts hepatitis E viruses (HEV), provisionally classified as members of the Caliciviridae family. Hepatitis E virus HEV the major etiologic agent of enterically transmitted non A non B hepatitis worldwide, is a spherical, non enveloped, single stranded RNA virus that is approximately 32nm-34nm in diameter. See image n1301705 on the site.

Colorized transmission electron micrograph of immature mpox virus particles (pink with orange viral envelope) found within an infected VERO E6 cell (green), cultured in the laboratory.

HIV-1. Transmission electron micrograph. Cone-shaped cores are sectioned in various orientations

Human herpes virus-6. Transmission electron micrograph (TEM) of human herpes virus-6 (HHV-6) previously called HBLV (human b-lymphotropic virus). It infects lymphocyte T cells as well. It is the cause of the childhood rash 'roseola' and some cases of mononucleosis.

Colorized transmission electron micrograph of mature extracellular Nipah virus particles (red) near the periphery of an infected VERO cell (yellow).

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